
Polynucleotides Treatments
Advanced Skin Regeneration Therapy
Skin Regeneration at Peonia Medical
Healthy skin is not treated in a single step. At Peonia Medical, we guide patients through a structured approach: Repair, Rebuild, and Maintain.
Before any advanced treatment, the skin must be stabilised. This stage focuses on reducing inflammation, restoring the skin barrier, and preparing the skin for regeneration.
• Medical-grade skincare (e.g. AlumierMD)
• Barrier repair protocols
• Gentle skin treatments (LED, calming facials)

Rebuild: Polynucleotide Therapy (Ameela® & Plinest®)
Once the skin is stable, we introduce regenerative treatments such as Polynucleotides to improve skin quality at a cellular level.
Polynucleotides (PN) are highly purified DNA fragments that:
- Stimulate collagen production
- Improve hydration and elasticity
- Support tissue repair
- Enhance overall skin quality
Indications:
- Fine lines and early ageing
- Dull or dehydrated skin
- Acne scarring and texture
- Under-eye rejuvenation
- Skin recovery post-laser
Treatment details:
- Duration: 30–45 minutes
- Method: micro-injections
- Downtime: minimal (small bumps 24–48h)
Results timeline:
- 2 weeks: improved hydration
- 4–6 weeks: smoother texture
- 8–12 weeks: collagen effect
Course:
- 2–3 sessions, 3–4 weeks apart
Products used:
- Ameela® (primary brand for facial treatment)
- Plinest® (additional regenerative option)

BOOK TODAY
Skin results require ongoing maintenance. This includes sun protection, medical skincare, and periodic treatments to preserve collagen and skin quality.
SPF | SKINCARE | MAINTENANCE
If you are unsure which stage your skin is currently in, our team will guide you through a personalised consultation.
CONTACT US

VAST experience
Peonia Medical is run by Dr Tracy Xu, an advanced aesthetic doctor and trainer with many years of experience.

Multiple clinics
Dr Tracy Xu works at professional clinics in Nottingham & London, also offering advanced aesthetic training.

Thermage FLX
We have the revolutionary Thermage FLX machine in the East Midlands, Yorkshire and Humber and North East area.
Reviews
Had my third CO2 treatment. So far I have been delighted with the results. Dr Tracey and her team are very professional and caring . Effective pain relief and comprehensive after care instructions are given. I would recommend Peonia Medical.
Kim H
Dr Tracy is lovely actually listens to your needs and is very knowledgeable, I went to see her for acne scarring and my skin is looking better than ever, can't thank her enough
Cat F
Had skin glow facial on 2nd of August by Anne-Marie, really enjoyed the treatment. Anne-Marie asked my skin routine before facial. I enjoyed the facial experience. I found Anne-Marie very tentative and professional. High recommended
Lia M
Dr Tracey and her assistant Scarlett , were very friendly and professional, ild definitely recommend her for treatment, I personally had xanthelasma removed on 4th may , many thanks Dr Tracy and Scarlett
Glynn B
Dr Tracy has been excellent, she takes time to explain things and has gone out of her way to answer my many questions along the way. She has always offered reassurance and taken time to explain the healing process of my treatment. All the staff are incredibly helpful and accommodating on the phone also
Sonya